Research Library
Welcome to The AERD Research Library
Browse our collection of publications and research about AERD. Knowledge is power - this is a great place to learn more about AERD and AERD treatments.
General Info & News
COVID-19 Pfizer & Moderna Vaccine Guidance for AERD Patients
Aspirin-Exacerbated Respiratory Disease - 2018 New England Journal of Medicine Article
2020 Brigham & Women's AERD Center Newsletter
2019 Brigham & Women's AERD Center Newsletter
2018 Brigham & Women's AERD Center Newsletter
2017 Brigham & Women's AERD Center Newletter
2016 Brigham & Women's AERD Center Newletter
Aspirin Desensitization
Immunologic Effects of Aspirin Desensitization and High Dose Aspirin Therapy in AERD - 2021 Study
Systematic Review of Outcomes for Endoscopic Sinus Surgery and Subsequent Aspirin Desensitization in AERD - 2020 Study
Aspirin Therapy in AERD: “One Size” Might Not Fit All - 2020 Editorial
Major Complications of Aspirin Desensitization and Maintenance Therapy in AERD - 2020 Study
Analysis of Spirometry Measurements as Predictors of Aspirin Desensitization Outcomes - 2019 Study
Aspirin Desensitization: Faster Protocols for Busy Patients - 2019 Article
Factors Correlated with Repeated Aspirin Dosing During Desensitization - 2018 Study
Outcomes after Complete Endoscopic Sinus Surgery and Aspirin Desensitization in AERD - 2018 Study
Safetey and Outcomes of Aspirin Desensitization - 2018 Study
Frequency & Severity of Reactions During Desensitization - 2017 Study
Nasal Ketorolac Challenge for AERD Diagnosis - 2017 Study
The Role of Aspirin Desensitization in the Management of AERD - 2017 Review
Predictive Factors of Reaction Severity During Aspirin Desensitization - 2016 Study
Alternative Aspirin Desensitization Protocol - 2015 Article
Aspirin Desensitization in AERD: Consideration of a New Oral Challenge Protocol - 2015 Editorial
The Clinical Dilemma of "Silent Desensitization" in AERD - 2013 Study
Rational Approach to Dosing During Oral Challenge & Desnsitization - 2009 Study
An Economic Analysis of Aspirin Desensitization - 2008 Study
650 Versus 1300mg Aspirin Daily for AERD Treatment - 2007 Study
Predicting Severity of Reactions During Aspirin Desensitization - 2007 Study
Characterization of Ocular Reactions During Aspirin Challenge - 2005 Study
Long Term Treatment With Aspirin in AERD/Samter's Triad Patients - 2003 Study
Biologic Medications
Immunology Based Recommendations for Available and Upcoming Biologics in AERD - 2021 Article
Dupilumab as Add-on Therapy for Chronic Rhinosinusitis With Nasal Polyposis in Aspirin Exacerbated Respiratory Disease - 2021 Study
A Multicenter Approach to Evaluate Omalizumab Effectiveness in Samter’s Triad- 2020 Study
Biologics in Chronic Rhinosinusitis with Nasal Polyposis - 2019 Study
Omalizumab Treatment in Samter's Triad: Case Series and Review of the Literature - 2019 Study
Aspirin Desensitization or Biologics for AERD? - 2019 Article
Omalizumab Can Inhibit Respiratory Reaction During Aspirin Desensitization - 2018 Study
Omalizumab (Xolair) in the Treatment of AERD - 2015 Letter
Effects of Omalizumab in Cases of Samter’s Syndrome - 2013 Article
Leukotriene Modifiers
Efficacy of Zileuton in Patients with Asthma and History of Aspirin Sensitivity - 2017 Study
Improvement of Aspirin-Intolerant Asthma by Montelukast, a Leukotriene Antagonist - 2002 Study
Treatment of Aspirin-Intolerant Asthma with Anti-Leukotrienes - 2000 Study
Benefits from Adding Zileuton (Zyflo) to Conventional Therapy in AERD Patients - 1998 Study
Surgery & Other Treatments
Appropriate Extent of Surgery for Aspirin Exacerbated Respiratory Disease - 2020 Study
Sinus Surgery Effects on Diagnosis and Management of Patients with AERD - 2019 Article
Is Topical High‐Volume Budesonide Sinus Irrigation Safe? - 2017 Review
Outcomes of Complete Versus Targeted Approaches to Endoscopic Sinus Surgery - 2015 Study
Safety and Effectiveness of Rinsing with Budesonide - 2014 Review
Revision Rates After Endoscopic Sinus Surgery: A Recurrence Analysis - 2011 Study
Canine Fossa Trephine is a Beneficial Procedure in Patients with Samter’s Triad - 2011 Study
Diet & Lifestyle
Alcohol Hypersensitivity In CRSwNP And Polyphenols - 2021 Study
Can Diet Modification Be an Effective Treatment in AERD? - 2018 Article
Dietary Fatty Acid Modification for the Treatment of AERD - 2017 Study
Brigham & Women's Omega Fatty Acid Diet Guidelines
Quitting Smoking as a Risk Factor for Developing AERD - 2017 Study
Activation of Basophils and Eosinophils By EtOH in Alcohol - 2017 Study
Low Salicylate Diet - 2015 Study
Alcohol-Induced Respiratory Symptoms Are Common in Patients With AERD - 2014 Study
Alcohol & Polyphenols - 2014 Letter
Smoking, Environmental Tobacco Smoke, and AERD - 2012 Study
Sodium Salicylate and Aspirin Disease - 1980 Study
Safety of Specific Pain Relievers
Safety of Celecoxib (Celebrex) in AERD Patients - 2002 Study
Reactions to Tylenol -1995 Study
Salsalate Cross-Sensitivity in Aspirin-Sensitive Patients with Asthma - 1990 Study
Other AERD Research
COVID-19 in a Series of Patients with Aspirin Exacerbated Respiratory Disease - 2021 Study
Endogenous Cannabinoids May Regulate Chronic Inflammation in AERD - 2020 Study
Aspirin Exacerbated Respiratory Disease: Update on Medical Management - 2020 Review Article
Inflammatory Heterogeneity in Aspirin Exacerbated Respiratory Disease - 2020 Study
AERD: Quo Vadis? - 2020 Editorial
Inflammatory Macrophage Memory in NSAID Exacerbated Respiratory Disease - 2020 Study
Differences in Men and Women Suffering from CRSwNP and AERD in Quality of Life - 2020 Study
Aural Polyps in Aspirin-Exacerbated Respiratory Disease - 2020 Study
Lipid Mediated Innate Lymphoid Cell Recruitment and Activation in AERD - 2020 Study
Is Otitis Media with Effusion Associated with Samter's Triad a New Nosological Entity? - 2020 Study
Leukotriene-Associated Rash in Aspirin-Exacerbated Respiratory Disease - 2020 Study
Does IgE Have a Role in Aspirin-Exacerbated Respiratory Disease?- 2020 Study
Inflammatory Macrophage Memory in NSAID-Exacerbated Respiratory Disease- 2020 Study
Perimenstrual Asthma in Aspirin-Exacerbated Respiratory Disease - 2019 Study
Do NERDy Eosinophils Accelerate Nasal Polyp Growth? - 2019 Study
Aspirin-Exacerbated Respiratory Disease: A Syndrome of Mast Cell-Mediated PgD2- 2019 Article
Aspirin Exacerbated Respiratory Disease: Epidemiology, Pathophysiology, and Management - 2019 Review
Aspirin-Exacerbated Respiratory Disease: Association of Sinus and Asthma Morbidity - 2019 Study
Nasal Challenge with Ketorolac: Utility and Safety in Clinical Practice - 2019 Study
Computed Tomography Findings in Patients with Samter’s Triad: an Observational Study - 2019 Study
Role of Periostin in Brazilian Patients with Aspirin Exacerbated Respiratory Disease - 2019 Study
Clinical Updates in Aspirin-Exacerbated Respiratory Disease - 2019 Review
Hearing Loss and Middle Ear Symptoms in Aspirin-Exacerbated Respiratory Disease - 2018 Study
Pathogenesis of NSAID-Induced Reactions in Aspirin-Exacerbated Respiratory Disease - 2018 Review
The Utility of Biomarkers in Diagnosis of Aspirin Exacerbated Respiratory Disease - 2018 Study
A Retrospective Analysis of Esophageal Eosinophilia in Patients with Aspirin ExacerbatedRespiratory Disease - 2018 Study
Aspirin-Exacerbated Respiratory Disease - 2018 Article
Depression Symptoms and Quality of Life Among Individuals with AERD - 2018 Study
Endocannabinoid Receptor CB2R is Significantly Expressed in AERD: A Pilot Study - 2018 Study
Nasal Polyp IgE and IgG4 Levels are Elevated in AERD Patients - 2018 Study
Role of Group 2 Innate Lymphocytes in AERD Pathogenesis - 2018 Article
Frequency of Anti-inflammatory Related Cutaneous Manifestation in Patients with AERD - 2018 Study
Association of AERD with Airway Mycosis - 2018 Study
Update on Aspirin-Exacerbated Respiratory Disease - 2017 Article
Potential Biomarkers for AERD Diagnosis - 2017 Study
Automated Identification of an Aspirin-Exacerbated Respiratory Disease Cohort - 2017 Study
Eosinophils and Mast Cells in Aspirin Exacerbated Respiratory Disease - 2016 Review
Genetic and Epigenetic Components of Aspirin Exacerbated Respiratory Disease - 2016 Study
Coronary Artery Vasospasm in AERD Patients - 2016 Study
AERD Prevalence, Diagnosis, Treatment, and Future Considerations - 2016 Review
Thymic Stromal Lymphopoietin Controls Prostaglandin D2 Generation in Patients with AERD - 2016 Study
Aspirin-Exacerbated Respiratory Disease -- New Prime Suspects - 2016 Article
Survey-Defined Patient Experiences With Aspirin-Exacerbated Respiratory Disease - 2015 Study
Low Dose Aspirin Tolerance Does Not Preclude AERD - 2015 Letter
Low Dose Aspirin Use Delays AERD Diagnosis - 2015 Study
Prevalence of Aspirin-Exacerbated Respiratory Disease Among Asthmatics - 2015 Study
Prostaglandin D2: A Dominant Mediator of AERD - 2015 Study
Platelets in Patients with Aspirin-Exacerbated Respiratory Disease - 2015 Review
How Patient Experiences Should Change Our Approach to Treating Patients with AERD - 2015 Editorial
Elevated Total Serum IgE in Nonatopic Patients with - AERD - 2014 Study
Otologic Manifestation of Samter Triad - 2014 Case Study
AERD (Samter's Triad) Subtypes - 2014 Study
Prominent Role of IFN-g in Patients with AERD - 2013 Study
Presenation of AERD (Samter's Triad) in a 13 Year Old - 2013 Case Report
Samter’s Triad and Eicosanoid Imbalance in Children with Recurrent Nasal Polyps - 2012 Article
Aspirin Sensitivity and Chronic Rhinosinusitis with Polyps: A Fatal Combination - 2012 Article
Expression of Melatonin in AERD/Samter's Triad Patients - 2011 Study
What Do We Know About the Genetics of Aspirin Intolerance? - 2008 Study
Otologic Manifestations of AERD (Samter's Triad) - 2007 Study
Natural History of Aspirin Induced Asthma - 2000 Study
Clinical Features and Diagnosis of Aspirin Induced Asthma - 2000 Study
Amalgam Allergy Associated with AERD Reactions - 1999 Case Study
Tryptase and Histamine Release During Aspirin-Induced Respiratory Reactions - 1991 Study
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